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Medical Letter (Medletter)
2023, Volume 1, Issue 4 : 1-5
Research Article
Clinical Outcomes Following Percutaneous Coronary Intervention: A Multicenter Evaluation of Procedural Success, Complications, and Long-Term Cardiovascular Outcomes
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1
Department of Interventional Cardiology, Global Institute of Medical Sciences, New York, USA
2
Department of Cardiovascular Medicine, European Heart Research Centre, Berlin, Germany
3
School of Clinical Medicine, International Medical University, London, United Kingdom
4
Department of Cardiology and Vascular Sciences, Pacific Healthcare University, Sydney, Australia
Abstract

Background

Percutaneous Coronary Intervention (PCI) has become a cornerstone in the treatment of coronary artery disease (CAD), offering rapid restoration of coronary blood flow and reducing morbidity and mortality associated with myocardial ischemia. Advances in stent technology, pharmacotherapy, and procedural techniques have substantially improved patient outcomes.

Objective

This study evaluates clinical outcomes following PCI, focusing on procedural success, major adverse cardiovascular events (MACE), mortality, restenosis, quality of life, and predictors of favorable outcomes.

Methods

A multicenter observational study was conducted involving 850 patients who underwent PCI for stable coronary artery disease or acute coronary syndrome. Clinical, procedural, and follow-up data were collected over a 12-month period. Statistical analyses included descriptive statistics, Kaplan–Meier survival analysis, and multivariate regression.

Results

Procedural success was achieved in 96.8% of cases. At 12 months, overall survival was 95.2%, while MACE occurred in 11.4% of patients. Drug-eluting stents demonstrated significantly lower restenosis rates compared to bare-metal stents (4.2% vs. 11.6%; p<0.001). Medication adherence and cardiac rehabilitation participation were significant predictors of improved outcomes.

Conclusion

PCI remains a highly effective treatment for coronary artery disease, with excellent procedural success and favorable long-term outcomes. Comprehensive post-procedural management significantly enhances survival and reduces cardiovascular complications.

 

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